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Gelatin-based hydrogels for biomedical applications

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Abstract

Gelatin-based hydrogels derived from hydrolysis of collagen have been extensively used in pharmaceutical and medical applications because of their biocompatibility and biodegradability. For example, gelatin-based hydrogels are finding use in drug delivery and tissue engineering because they are able to promote cell adhesion and proliferation. In addition, these hydrogels can be used as wound dressings due to their attractive fluid absorbance properties. Manufacturing technologies such as ultraviolet stereolithography and two-photon polymerization can be used to prepare structures containing photosensitive gelatin-based hydrogels. This review describes the preparation of gelatin-based hydrogels and use of these materials for biomedical applications.

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Acknowledgments

The authors would like to acknowledge support from the US National Institutes of Health (5 R21 AI117748 02).

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Authors and Affiliations

  1. Department of Material Science & Engineering, North Carolina State University, Box 7907, Raleigh, NC, 27695, USA

    Panupong Jaipan & Roger J. Narayan

  2. Joint Department of Biomedical Engineering, University of North Carolina and North Carolina State University, Box 7115, Raleigh, NC, 27695, USA

    Alexander Nguyen & Roger J. Narayan

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  1. Panupong Jaipan
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  2. Alexander Nguyen
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  3. Roger J. Narayan
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Correspondence to Roger J. Narayan.

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Jaipan, P., Nguyen, A. & Narayan, R.J. Gelatin-based hydrogels for biomedical applications. MRS Communications 7, 416–426 (2017). https://doi.org/10.1557/mrc.2017.92

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