Famotidine
| Subclass of | H2 antagonists  |
|---|---|
| Get use | Medication |
| Chemical formula | C₈H₁₅N₇O₂S₃ |
| Canonical SMILES | C1=C(N=C(S1)N=C(N)N)CSCCC(=NS(=O)(=O)N)N |
| Isomeric SMILES | C1=C(N=C(S1)N=C(N)N)CSCC/C(=N/S(=O)(=O)N)/N |
| Active ingredient in | Pepcid, Calmicid |
| World Health Organisation international non-proprietary name | famotidine |
| Significant drug interaction | posaconazole, dasatinib monohydrate, pazopanib, ketoconazole |
| Pregnancy category | Australian pregnancy category B1, US pregnancy category B |
| LiverTox likelihood score | LiverTox toxicity likelihood category C |
| Get characteristic | bitterness |
| Subject has role | H2 antagonists, anti-ulcer drug |
Famotidine, dem sell under de brand name Pepcid among odas, be a histamine H2 receptor antagonist medication wey dey decrease stomach acid production.[1] E be used to treat peptic ulcer disease, gastroesophageal reflux disease, den Zollinger–Ellison syndrome.[1] Dem dey take am by mouth anaa by injection into a vein.[1] E dey begin dey work within an hour.[1]
Common side effects dey include headache, abdominal pain, diarrhea anaa constipation, den dizziness.[1] Serious side effects fi include pneumonia den seizures.[1][2] Ein use insyd pregnancy dey appear safe buh e no be well studied, while use during breastfeeding no be recommended.[3]
Dem patent famotidine insyd 1979 wey e cam into medical use insyd 1985.[4] E be available as a generic medication.[5] Insyd 2023, na e be de 33rd most commonly prescribed medication insyd de United States, plus more dan 16 million prescriptions.[6][7]
References
[edit | edit source]- 1 2 3 4 5 6 "Famotidine Monograph for Professionals". Drugs.com. American Society of Health-System Pharmacists. Archived from the original on 17 June 2019. Retrieved 3 March 2019.
- ↑ British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. pp. 74–75. ISBN 9780857113382.
- ↑ "Famotidine Pregnancy and Breastfeeding Warnings". Drugs.com. Archived from the original on 16 December 2023. Retrieved 3 March 2019.
- ↑ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 444. ISBN 9783527607495. Archived from the original on 29 July 2020. Retrieved 7 May 2020.
- ↑ British national formulary : BNF 76 (76 ed.). Pharmaceutical Press. 2018. pp. 74–75. ISBN 9780857113382.
- ↑ "Top 300 of 2023". ClinCalc. Archived from the original on 12 August 2025. Retrieved 12 August 2025.
- ↑ "Famotidine Drug Usage Statistics, United States, 2014 - 2023". ClinCalc. Retrieved 17 August 2025.
External links
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