ACSM2B

ACSM2B
Pengidentifikasi
Alias	ACSM2B, ACSM2, HXMA, HYST1046, acyl-CoA synthetase medium-chain family member 2B, acyl-CoA synthetase medium chain family member 2B
ID Eksternal	OMIM: 614359; MGI: 2385289; HomoloGene: 89289; GeneCards: ACSM2B; OMA:ACSM2B - orthologs
Nomor EC	6.2.1.25 6.2.1.2, 6.2.1.25
Lokasi gen (Manusia) Kr. Kromosom 16 (manusia) Pita 16p12.3 Awal 20,536,226 pb Akhir 20,576,427 pb
Pola ekspresi RNA Bgee Manusia Tikus (ortologi) Ekspresi tertinggi di right lobe of liver renal cortex human kidney Testis Gonad epithelium of colon sural nerve left uterine tube renal medulla muscle of thigh Ekspresi tertinggi di right kidney Tubulus proksimal human kidney primary visual cortex morula muscle of thigh Folikel rambut Zigot superior frontal gyrus renal corpuscle Referensi data ekspresi selengkapnya BioGPS Data ekspresi referensi lebih lanjut
Ontologi gen Fungsi molekuler nucleotide binding ligase activity catalytic activity ATP binding metal ion binding butyrate-CoA ligase activity CoA-ligase activity fatty-acyl-CoA synthase activity fatty acid ligase activity fungsi molekuler Komponen seluler mitokondria Matriks mitokondria Proses biologis xenobiotic metabolic process Metabolisme Metabolisme asam lemak metabolisme lipid fatty acid biosynthetic process acyl-CoA metabolic process Sumber:Amigo / QuickGO
Ortologi Spesies Manusia Tikus Entrez 348158 233799 Ensembl ENSG00000066813 ENSMUSG00000030945 UniProt Q68CK6 Q8K0L3 RefSeq (mRNA) NM_001105069 NM_182617 NM_001177977 NM_001177978 NM_146197 RefSeq (protein) NP_001098539 NP_872423 NP_001171448 NP_001171449 NP_666309 Location (UCSC) Chr 16: 20.54 – 20.58 Mb n/a PubMed search
Wikidata
Lihat/Sunting Manusia Lihat/Sunting Tikus

Acyl-CoA synthetase medium-chain family member 2B (ACSM2B) adalah enzim mitokondria yang pada manusia disandi oleh gen ACSM2B.

Pranala luar

• Lokasi genom ACSM2B manusia dan halaman rincian gen ACSM2B dalam UCSC Genome Browser.

Bacaan lebih lanjut

• Lindner I, Rubin D, Helwig U, et al. (2006). "The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population". Mol Nutr Food Res. 50 (3): 270–4. doi:10.1002/mnfr.200500241. PMID 16521160.
• Yamada S, Ohira M, Horie H, et al. (2004). "Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas". Oncogene. 23 (35): 5901–11. doi:10.1038/sj.onc.1207782. PMID 15221005.
• Vessey DA, Kelley M, Warren RS (2004). "Characterization of triacsin C inhibition of short-, medium-, and long-chain fatty acid: CoA ligases of human liver". J. Biochem. Mol. Toxicol. 18 (2): 100–6. doi:10.1002/jbt.20009. PMID 15122652. S2CID 8154380.{{cite journal}}: Pemeliharaan CS1: DOI bebas tanpa ditandai (link)
• Vessey DA, Kelley M (2001). "Characterization of the reaction mechanism for the XL-I form of bovine liver xenobiotic/medium-chain fatty acid:CoA ligase". Biochem. J. 357 (Pt 1): 283–8. doi:10.1042/0264-6021:3570283. PMC 1221953. PMID 11415461.
• Vessey DA, Kelley M, Warren RS (1999). "Characterization of the CoA ligases of human liver mitochondria catalyzing the activation of short- and medium-chain fatty acids and xenobiotic carboxylic acids". Biochim. Biophys. Acta. 1428 (2–3): 455–62. doi:10.1016/s0304-4165(99)00088-4. PMID 10434065.
• Vessey DA, Hu J (1997). "Isolation from bovine liver mitochondria and characterization of three distinct carboxylic acid: CoA ligases with activity toward xenobiotics". J. Biochem. Toxicol. 10 (6): 329–37. doi:10.1002/jbt.2570100608. PMID 8934636.{{cite journal}}: Pemeliharaan CS1: DOI bebas tanpa ditandai (link)
• Vessey DA, Hu J, Kelley M (1997). "Interaction of salicylate and ibuprofen with the carboxylic acid: CoA ligases from bovine liver mitochondria". J. Biochem. Toxicol. 11 (2): 73–8. doi:10.1002/(SICI)1522-7146(1996)11:2<73::AID-JBT4>3.0.CO;2-R. PMID 8884467.