Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2003 Aug 2:3:677-83.
doi: 10.1100/tsw.2003.53.

Volume transmission and pain perception

Gilberto C Castañeda-Hernández  1 , Paul Bach-y-Rita
Affiliations
Review

Volume transmission and pain perception

Gilberto C Castañeda-Hernández et al. ScientificWorldJournal. .

Abstract

Volume transmission (VT) is the diffusion through the brain extracellular fluid of neurotransmitters released at points that may be remote from the target cells with the resulting activation of extrasynaptic receptors. VT appears to play multiple roles in the brain in normal and abnormal activity, brain plasticity and drug actions. The relevance of VT to pain perception has been explored in this review.

PubMed Disclaimer

Substances

LinkOut - more resources