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Sarcoidosis is a multisystem granulomatous disorder of unknown etiology that primarily affects the lungs and lymphoid organs. Additional organs may become involved over time. Sarcoidosis was first reported in 1877 and remains a concern for clinicians and pathologists. The disease may remain silent, and most patients remain asymptomatic for a prolonged period. Patients may later present with nonspecific symptoms or organ failure. Sarcoidosis is a challenging diagnosis for clinicians, and histopathology remains the gold standard for diagnosis.
Rossides M, Darlington P, Kullberg S, Arkema EV. Sarcoidosis: Epidemiology and clinical insights. J Intern Med. 2023 Jun;293(6):668-680.
-
PubMed
Weeratunga P, Moller DR, Ho LP. Immune mechanisms of granuloma formation in sarcoidosis and tuberculosis. J Clin Invest. 2024 Jan 02;134(1)
-
PMC
-
PubMed
Chauhan A, Jandial A, Mishra K, Sandal R. Acute arthritis, skin rash and Lofgren's syndrome. BMJ Case Rep. 2021 Jun 07;14(6)
-
PMC
-
PubMed
Tana C, Donatiello I, Caputo A, Tana M, Naccarelli T, Mantini C, Ricci F, Ticinesi A, Meschi T, Cipollone F, Giamberardino MA. Clinical Features, Histopathology and Differential Diagnosis of Sarcoidosis. Cells. 2021 Dec 26;11(1)
-
PMC
-
PubMed
Koneti J, Cherukuri SP, Gadde S, Kalluru R, Chikatimalla R, Dasaradhan T. Sarcoidosis and Its Dermatological Manifestations: A Narrative Review. Cureus. 2022 Aug;14(8):e28053.
-
PMC
-
PubMed
