2021
Mol* Viewer: modern web app for 3D visualization and analysis of large biomolecular structures
Abstract: Large biomolecular structures are being determined experimentally on a daily basis using established techniques such as crystallography and electron microscopy. In addition, emerging integrative or hybrid methods (I/HM) are producing structural models of huge macromolecular machines and assemblies, sometimes containing 100s of millions of non-hydrogen atoms. The performance requirements for visualization and analysis tools delivering these data are increasing rapidly. Significant progress in developing online,…
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“…18 Additionally, protein structure prediction by sequence alignments for homology modeling 22 suggests alteration of the 3D structure of NS7a of KMUH-8 compared with that of wild-type (Figure S4). 23 Wild-type NS7a contains seven β-strands (Figure S4A), which is similar to the results obtained by x-ray crystallography. 18 The predicted KMUH-8 NS7a includes only two β-strands (Figure S4B), with possible loss of function as an interferon antagonist.…”
Section: Discussion
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confidence: 85%