Oxyresveratrol
| Names | |
|---|---|
| Preferred IUPAC name
4-[(E)-2-(3,5-Dihydroxyphenyl)ethen-1-yl]benzene-1,3-diol | |
| Other names
2,3',4,5'-Tetrahydroxy-trans-stilbene | |
| Identifiers | |
3D model (JSmol) |
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| ChemSpider | |
| ECHA InfoCard | 100.108.380 |
| KEGG | |
| MeSH | C034912 |
PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C14H12O4 | |
| Molar mass | 244.24 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Oxyresveratrol is a stilbenoid found in several plant species. It is found in only one gymnosperm (Gnetum hainensis), but in several angiosperm (particularly in the genera Artocarpus and Morus).[1] Oxyresveratrol is found in the traditional Thai drug 'Puag-Haad', which is made from the heartwood of Artocarpus lakoocha.[2] It is also the aglycone of mulberroside A, a compound found in Morus alba, the white mulberry.[3]
Oxyresveratrol is a potent tyrosinase inhibitor,[3] which also exhibits neuroprotective and antioxidant properties.[1] It is being studied for potential applications in treating neurological diseases like stroke, Alzheimer's disease, and Parkinson's disease, as well as for its potential anticancer and antimicrobial effects.[1] It is light sensitive, and will degrade on exposure to UV radiation.[1]
References
[edit]- 1 2 3 4 Likhitwitayawuid, Kittisak (2021-07-11). "Oxyresveratrol: Sources, Productions, Biological Activities, Pharmacokinetics, and Delivery Systems". Molecules. 26 (14): 4212. doi:10.3390/molecules26144212. ISSN 1420-3049. PMC 8307110. PMID 34299485.
- ↑ Maneechai, S; Likhitwitayawuid, K; Sritularak, B; Palanuvej, C; Ruangrungsi, N; Sirisa-Ard, P (2009). "Quantitative analysis of oxyresveratrol content in Artocarpus lakoocha and 'Puag-Haad'". Medical Principles and Practice. 18 (3): 223–7. doi:10.1159/000204354. PMID 19349726. S2CID 29232919.
- 1 2 Kim, JK; Kim, M; Cho, SG; Kim, MK; Kim, SW; Lim, YH (2010). "Biotransformation of mulberroside a from Morus alba results in enhancement of tyrosinase inhibition". Journal of Industrial Microbiology & Biotechnology. 37 (6): 631–7. doi:10.1007/s10295-010-0722-9. PMID 20411402. S2CID 21236818.
